8-Azabicyclo[3.2.1]octan-3-ol → (3-Hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-[3-(tetrahydro-pyran-4-ylmethoxy)-phenyl]-methanone

HRID 391223

반응식

HRID 391223 반응식
[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][O:8][C:9]2[CH:10]=[C:11]([CH:15]=[CH:16][CH:17]=2)[C:12]([OH:14])=O)[CH2:3][CH2:2]1.[CH:18]12[NH:25][CH:22]([CH2:23][CH2:24]1)[CH2:21][CH:20]([OH:26])[CH2:19]2>>[OH:26][CH:20]1[CH2:19][CH:18]2[N:25]([C:12]([C:11]3[CH:15]=[CH:16][CH:17]=[C:9]([O:8][CH2:7][CH:4]4[CH2:3][CH2:2][O:1][CH2:6][CH2:5]4)[CH:10]=3)=[O:14])[CH:22]([CH2:23][CH2:24]2)[CH2:21]1

참가 물질

3

반응물 2

HCID 681478-Azabicyclo[3.2.1]octan-3-olHCID 288754893-(Tetrahydro-2H-pyran-4-ylmethoxy)benzoic Acid

생성물 1

HCID 25242343(3-Hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-[3-(tetrahydro-pyran-4-ylmethoxy)-phenyl]-methanone

실험 절차

Prepared from 3-(tetrahydro-pyran-4-yl-methoxy)-benzoic acid and 8-aza-bicyclo[3.2.1]octan-3-ol. LC-MS (m/z): 346 (M+1).

출처 및 근거

ORD 기록
ord-3290a8a002614433bdaa076aa9b7f8e7
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383820B2

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