8-Azabicyclo[3.2.1]octan-3-ol → (3-Hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-{3-[2-(tetrahydro-pyran-4-yl)-ethoxy]-phenyl}-methanone

HRID 391224

반응식

HRID 391224 반응식
[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][CH:18]=2)[C:13]([OH:15])=O)[CH2:3][CH2:2]1.[CH:19]12[NH:26][CH:23]([CH2:24][CH2:25]1)[CH2:22][CH:21]([OH:27])[CH2:20]2>>[OH:27][CH:21]1[CH2:20][CH:19]2[N:26]([C:13]([C:12]3[CH:16]=[CH:17][CH:18]=[C:10]([O:9][CH2:8][CH2:7][CH:4]4[CH2:3][CH2:2][O:1][CH2:6][CH2:5]4)[CH:11]=3)=[O:15])[CH:23]([CH2:24][CH2:25]2)[CH2:22]1

참가 물질

3

반응물 2

HCID 681478-Azabicyclo[3.2.1]octan-3-olHCID 583476373-(Tetrahydro-pyran-4-ylethoxy)-benzoic acid

생성물 1

HCID 25242344(3-Hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-{3-[2-(tetrahydro-pyran-4-yl)-ethoxy]-phenyl}-methanone

실험 절차

Prepared from 3-(tetrahydro-pyran-4-yl-ethoxy)-benzoic acid and 8-aza-bicyclo[3.2.1]octan-3-ol. LC-MS (m/z): 360 (M).

출처 및 근거

ORD 기록
ord-2756bbb9150e415b9858d504d09fab7b
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383820B2

연결된 노트

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