Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(4-Aminophenyl)-1-propanol → (2e,4e,6e,8e)-3,7-Dimethyl-n-(pyridin-4-yl)-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(4-Aminophenyl)-1-propanol | HCID 235875 | — |
| 반응물 | Retinoic Acid | HCID 444795 | — |
| 반응물 | Edc hobt | HCID 86583742 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (2e,4e,6e,8e)-3,7-Dimethyl-n-(pyridin-4-yl)-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide | HCID 59539418 | — |
반응 단계
Coupling of (4-amino)phenylpropanol (453 mg; 3 mmol) and retinoic acid (600 mg, 2 mmol) in anhydrous DMF (4 mL) using standard EDC/HOBt coupling condtions yielded the desired amide as a pale, yellow solid (600 mg, 69%). EMS m/z: 434 ([M+1]+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383836B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-a39325d79a5a4919aba96709be717534 |
| 출처 메모 | uspto-grants-2013_02 |