Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Bromo-5-nitrophenyl)methanol → (3-Amino-5-bromophenyl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Bromo-5-nitrophenyl)methanol | HCID 14866972 | — |
| 촉매 | Adams' catalyst | HCID 345198 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (3-Amino-5-bromophenyl)methanol | HCID 58993589 | — |
반응 단계
(3-Bromo-5-nitrophenyl)methanol (3.9 g, 16.8 mmol) in methanol (35 mL) was flushed with nitrogen, and treated with platinum (IV) oxide (390 mg). The flask was flushed with hydrogen and allowed to stir under an atmosphere of hydrogen for 1 h. The reaction was flushed with nitrogen, filtered through celite, and concentrated to afford 3.1 g (94%). 1H-NMR (CDCl3, 300 MHz) δ 6.95 (s, 1H), 6.80 (s, 1H), 6.79 (s, 1H), 4.61 (s, 2H). Mass spec.: 203.96 (MH)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383821B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-e4f63e5b3b20495b971be59e1fb5bc9b |
| 출처 메모 | uspto-grants-2013_02 |