Methanol → HCID 68504560, 화합물

반응식

S(=O)(=O)(O)O.[CH2:6]([C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH2:15][CH3:16])[C:9]=1[CH2:17][C:18]([OH:20])=[O:19])[CH3:7].[CH3:21]O>>[CH2:6]([C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH2:15][CH3:16])[C:9]=1[CH2:17][C:18]([O:20][CH3:21])=[O:19])[CH3:7]

참가 물질

반응물 3

HCID 887Methanol

HCID 1118Sulfuric Acid

HCID 595382482-(2,6-Diethyl-4-methylphenyl)acetic acid

생성물 1

HCID 68504560HCID 68504560, 화합물

실험 절차

1 ml of concentrated sulfuric acid is added to 18.0 g (87.3 mmol) of 2,6-diethyl-4-methylphenylacetic acid and 300 ml of absolute methanol, and the mixture is heated at reflux for 4 h. After cooling, the mixture is extracted with ethyl acetate, the extracts are washed with water in sodium carbonate solution and dried (magnesium sulfate) and the solvent is distilled off. This gives 18.37 g of (95%) of the desired product as a colorless oil.