Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(4-Iodophenyl)ethan-1-one → (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(4-Iodophenyl)ethan-1-one | HCID 72869 | — |
| 반응물 | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| 생성물 | (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953842 | 86% |
반응 단계
In a manner similar to that describe in Example 434 a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 4-iodoacetophenone were reacted to give the title compound as a light yellow foam (52 mg, 86%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383825B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-81b5eb7fe2d143c6900463b22a74d1ce |
| 출처 메모 | uspto-grants-2013_02 |