Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Iodobenzoic acid → (S)-4-{[5-({[methyl(oxo)phenyl-lambda6-sulfanylidene]amino}carbonyl)pyridin-3-yl]ethynyl}benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Iodobenzoic acid | HCID 12085 | — |
| 반응물 | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| 생성물 | (S)-4-{[5-({[methyl(oxo)phenyl-lambda6-sulfanylidene]amino}carbonyl)pyridin-3-yl]ethynyl}benzoic acid | HCID 24953845 | 49% |
반응 단계
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 4-iodobenzoic acid were reacted to give the title compound as a light yellow solid (30 mg, 49%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383825B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-649b2d01dafa46669fb54909a51f23a2 |
| 출처 메모 | uspto-grants-2013_02 |