Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-iodo-1H-imidazole → (S)-5-(1H-imidazol-5-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-iodo-1H-imidazole | HCID 606522 | — |
| 반응물 | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| 생성물 | (S)-5-(1H-imidazol-5-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24954181 | 46% |
반응 단계
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 5-iodo-1H-imidazole were reacted to give the title compound as a white foam (24 mg, 46%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383825B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-36407a5c78d0444593bbcec4ff21248d |
| 출처 메모 | uspto-grants-2013_02 |