Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 391997노트

반응식

HRID 391997 반응식
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

생성물 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vaccuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

후처리

  1. customSolvents were evaporated
  2. customdried under vaccuo

출처 및 근거

ORD 기록
ord-326750fd2a7e4eabb6511a9907fdbeda
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383644B2

반응 노트

불러오는 중…