6-[(2-Aminoethyl)amino]pyridine-3-carbonitrile → HCID 69710004, 화합물

반응식

[C:1]([N:4]1[CH2:25][CH2:24][C:7]2[N:8]=[C:9](S(C)(=O)=O)[N:10]=[C:11]([C:12]3[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=3[Cl:19])[C:6]=2[CH2:5]1)(=[O:3])[CH3:2].[NH2:26][CH2:27][CH2:28][NH:29][C:30]1[CH:35]=[CH:34][C:33]([C:36]#[N:37])=[CH:32][N:31]=1>>[C:1]([N:4]1[CH2:25][CH2:24][C:7]2[N:8]=[C:9]([NH:26][CH2:27][CH2:28][NH:29][C:30]3[N:31]=[CH:32][C:33]([C:36]#[N:37])=[CH:34][CH:35]=3)[N:10]=[C:11]([C:12]3[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=3[Cl:19])[C:6]=2[CH2:5]1)(=[O:3])[CH3:2]

참가 물질

반응물 2

HCID 113694056-[(2-Aminoethyl)amino]pyridine-3-carbonitrile

HCID 69709723HCID 69709723, 화합물

생성물 1

HCID 69710004HCID 69710004, 화합물

실험 절차

Following Example 7, reaction of 6-acetyl-4-(2,4-dichlorophenyl)-2-(methylsulfonyl)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine and 2-(2-aminoethyl-amino)-5-cyanopyridine gave 6-[(2-{[6-acetyl-4-(2,4-dichlorophenyl)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile.

출처 및 근거

ORD 기록: ord-173f23d84f5f43b5a24b295752d3fa0b
출처 데이터셋: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06800632B2

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