Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 2-Oxoethyl butyrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 2,2-Dimethoxyethyl butyrate | HCID 11367300 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Oxoethyl butyrate | HCID 9898831 | — |
반응 단계
Compound 43a (176 mg, 1.0 mmol) was dissolved in 8 mL of CH2Cl2 and 4 mL of TFA (containing 5% H2O) was added. The mixture was stirred for 30 min at room temperature. The solution was then concentrated in vacuo to give the product 44a that was used immediately for the next step. 1H NMR (400 MHz, CDCl3) δ 0.92 (m, 3H), 1.64 (m, 2H), 2.24 (t, J=7.04 Hz, 2H), 4.72 (s, 2H), 9.60 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524691B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-8994c8ce8da447d3a3b5ecdf901c759e |
| 출처 메모 | uspto-grants-2013_09 |