Nitrilotriacetic Acid → 6-Amino-2-[bis(carboxymethyl)amino]hexanoic acid

반응식

[N:1]([CH2:10][C:11]([OH:13])=[O:12])([CH2:6][C:7]([OH:9])=[O:8])[CH2:2][C:3]([OH:5])=[O:4].[NH2:14][C@H:15](C(O)=O)[CH2:16][CH2:17][C:18](O)=O>>[NH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH:10]([N:1]([CH2:2][C:3]([OH:5])=[O:4])[CH2:6][C:7]([OH:9])=[O:8])[C:11]([OH:13])=[O:12]

참가 물질

반응물 2

HCID 8758Nitrilotriacetic Acid

HCID 33032L-Glutamic Acid

생성물 1

HCID 27352966-Amino-2-[bis(carboxymethyl)amino]hexanoic acid

실험 절차

Compound 11 is prepared using a procedure analogous to the procedure of Example 5 for the preparation of Compound 7, except that glutamic acid is used instead of N-(5-amino-1-carboxypentyl)iminodiacetic acid.

출처 및 근거

ORD 기록: ord-a26b8fdec8374cfc8cdd6e1eb991ba8c
출처 데이터셋: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06800765B2

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