Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Phenylenediamine → ethyl 2-(1H-1,3-benzodiazol-2-yl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Phenylenediamine | HCID 7243 | — |
| 반응물 | Ethyl 3-ethoxy-3-iminopropionate hydrochloride | HCID 75345 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | ethyl 2-(1H-1,3-benzodiazol-2-yl)acetate | HCID 308071 | — |
반응 단계
A solution of 1,2-phenylenediamine (1.0 eq) and ethyl 3-ethoxy-3-iminopropanoate hydrochloride (1.3 eq) in ethanol was stirred at 90° C. overnight. The reaction was cooled to room temperature and the solvent was removed in vacuo. Water and CH2Cl2 were added to the residue. The organic layer was separated, dried over Na2SO4 and the solvent removed. The solid recovered was used without purification. LC/MS m/z 205.2 (MH+), Rf 1.44 minutes.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06800760B2 |
| 출처 데이터셋 | uspto-grants-2004_10 |
| ORD ID | ord-0a0a45617ce141bc9ed3ed9c77d5f347 |
| 출처 메모 | uspto-grants-2004_10 |