Benzophenone → (2-Chlorophenyl)diphenylmethanol

HRID 392682

반응식

HRID 392682 반응식
[Mg].Br[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[Cl:9].[C:10]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)(=[O:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[Cl:9][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[C:10]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[OH:17]

참가 물질

4

반응물 3

HCID 3102BenzophenoneHCID 127541-Bromo-2-chlorobenzeneHCID 5462224Magnesium

생성물 1

HCID 298659(2-Chlorophenyl)diphenylmethanol수율 64%

실험 절차

Following the procedure outlined in Example 1, 1.3 g (52 mmol) of magnesium turnings, 10.0 g (52 mmol) of 1-bromo-2-chlorobenzene and 9.4 g (52 mmol) benzophenone gave 9.81 g (64%) of (2-Chlorophenyl) diphenyl methanol (Compound T3), mp: 91° C.

출처 및 근거

ORD 기록
ord-9f751d9353c94c38a888e18c2cc7f7e4
출처 데이터셋
uspto-grants-2004_10
특허 번호
US06803375B1

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