2,2-Diphenylacetyl chloride → N-(5-Ethyl-oxazol-2-yl)-2,2-diphenyl-acetamide

반응식

[CH2:1]([C:3]1[O:7][C:6]([NH2:8])=[N:5][CH:4]=1)[CH3:2].[C:9]1([CH:15]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:16](Cl)=[O:17])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH2:1]([C:3]1[O:7][C:6]([NH:8][C:16](=[O:17])[CH:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[N:5][CH:4]=1)[CH3:2]

참가 물질

반응물 2

HCID 746372,2-Diphenylacetyl chloride

HCID 226610805-Ethyl-2-oxazolamine

생성물 1

HCID 9796553N-(5-Ethyl-oxazol-2-yl)-2,2-diphenyl-acetamide

실험 절차

The title compound, white solid, m.p. 148-149° C. and MS: m/e=307.3 (M+H+) was prepared in accordance with the general method of example 44a from 5-ethyl-oxazol-2-ylamine and 2,2-diphenylacetic acid chloride.

출처 및 근거

ORD 기록: ord-bae7bcf1f1914c8fa7f6a416f442124e
출처 데이터셋: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06803381B1

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