Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Stannous Chloride → 4-Benzyloxy-2-fluorophenylhydrazine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Stannous Chloride | HCID 24479 | — |
| 반응물 | 4-(Benzyloxy)-2-fluoroaniline | HCID 11499809 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Benzyloxy-2-fluorophenylhydrazine hydrochloride | HCID 11637567 | 77.2% |
반응 단계
A solution of NaNO2 (1.38 g) in H2O (8 mL) was added to a suspension of 4-benzyloxy-2-fluoroaniline (5.0 g) in 6N HCl (24 mL) at 0° C. After 30 minutes stirring, a solution of SnCl2 (7.7 g) in 6N HCl (24 mL) was added to the mixture at 0° C. The mixture was allowed to warm to room temperature and stirred for 1.5 hours to produce a precipitate. The precipitate was collected by filtration to yield 4.15 g of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06803372B2 |
| 출처 데이터셋 | uspto-grants-2004_10 |
| ORD ID | ord-5fd2936fa3204d8a9f9999cf28a8ea6b |
| 출처 메모 | uspto-grants-2004_10 |