Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl chloride → N-biphenyl-3-ylmethyl-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | 3-(Aminomethyl)biphenyl | HCID 2760368 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-biphenyl-3-ylmethyl-acetamide | HCID 22660935 | 128.5% |
반응 단계
C-Biphenyl-3-yl-methylamine (700 mg, 3.8 mmol) was dissolved in 38 mL of CH2Cl2. To this was added 38 mL of satd NaHCO3 (aq) followed by acetyl chloride (1.41 mL 19,8 mmol). The resulting mixture was stirred 45 min. The organic layer was separated, washed with satd NaCl, dried over Na2SO4, filtered and solvent removed under vacuum to yield 1.1 grams of N-biphenyl-3-ylmethyl-acetamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06803378B2 |
| 출처 데이터셋 | uspto-grants-2004_10 |
| ORD ID | ord-dedfeb76dab54b4b9c853a25bd0c6433 |
| 출처 메모 | uspto-grants-2004_10 |