3,4-Dichloroaniline → HCID 693064, 화합물

반응식

[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[Cl:11][C:12]1[CH:13]=[C:14]([CH:16]=[CH:17][C:18]=1[Cl:19])[NH2:15]>>[Cl:11][C:12]1[CH:13]=[C:14]([NH:15][C:6](=[O:7])[C:5]2[CH:9]=[CH:10][C:2]([F:1])=[CH:3][CH:4]=2)[CH:16]=[CH:17][C:18]=1[Cl:19]

참가 물질

반응물 2

HCID 72573,4-Dichloroaniline

HCID 678794-Fluorobenzoyl chloride

생성물 1

HCID 693064HCID 693064, 화합물

실험 절차

Reaction of 4-fluorobenzoyl chloride with 3,4-dichloroaniline using Method II, step 1, gave the title amide as crystals: mp 160-161° C. (ethyl acetate-hexane). 1HNMR 400 MHz (CDCl3) δ (ppm): 7.19 (2H, m, aromatics), 7.44 (2H, m, aromatics), 7.70 (1H, broad, NH), 7.88 (3H, m, aromatics). Anal. Calcd for C13H18Cl2FNO: C, 54.96; H, 2.84; N, 4.93. Found: C, 54.96; H, 2.87; N, 4.90.

출처 및 근거

ORD 기록: ord-d30041f089b2416a9f1ba66641a7e96e
출처 데이터셋: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06803378B2

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