Di-tert-butyl dicarbonate → 3-(N,N-dimethylcarbamoyl)-2,6-dimethylphenylisocyanate

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A solution of di-tert-butyl dicarbonate (0.081 g) in methylene chloride (1.6 ml) and a solution of 3-amino-N,N,2,4-tetramethylbenzamide (J. Chem. Soc., Perkin Trans, I. 1973, 1-4; 0.072 g) in methylene chloride (1.0 ml) were added in turn to a solution of 4-diethylaminopyridine (0.004 g) in methylene chloride (0.4 ml). The resultant mixture was stirred at ambient temperature for 20 minutes. There was thus obtained a solution of 3-(N,N-dimethylcarbamoyl)-2,6-dimethylphenylisocyanate which was used without further purification.

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