4-Methoxy-3-(2-methoxyethoxy)nitrobenzene → 4-Methoxy-3-(2-methoxyethoxy)aniline
반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[O:12][CH2:13][CH2:14][O:15][CH3:16]>[Pd].C(OCC)(=O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][C:4]=1[O:12][CH2:13][CH2:14][O:15][CH3:16]참가 물질
4
실험 절차
A mixture of 4-methoxy-3-(2-methoxyethoxy)nitrobenzene (7 g, 30 mmol) and 10% palladium-on-charcoal catalyst (1.4 g) in ethyl acetate (70 ml) was stirred under hydrogen at 3.3 atmospheres pressure for 1 hour. The catalyst was removed by filtration through diatomaceous earth and the solvent removed by evaporation. The solid residue was suspended in ethyl acetate, collected by filtration and dried under vacuum to give 4-methoxy-3-(2-methoxyethoxy)aniline (6.1 g, 100%).
후처리
- customThe catalyst was removed by filtration through diatomaceous earth
- customthe solvent removed by evaporation
- filtrationcollected by filtration
- customdried under vacuum
출처 및 근거
- ORD 기록
- ord-aadfa82b400f4cbfbc72208da66c4116
- 출처 데이터셋
- uspto-grants-2004_10
- 특허 번호
- US06809097B1
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