Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Nitrophenyl)acetic acid → Benzeneacetyl chloride, 4-nitro-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Nitrophenyl)acetic acid | HCID 4661 | — |
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Benzeneacetyl chloride, 4-nitro- | HCID 6452210 | — |
반응 단계
3.75 ml (7.5 mmoles) of a 2M solution of oxalyl chloride in dichloromethane is added at 20° C. to a solution of 0.9 g (5 mmoles) of 4-nitrophenylacetic acid in a mixture composed of 10 ml of dichloromethane and 0.5 ml of DMF. After agitation for 30 minutes, the solution is concentrated under vacuum. The yellow oil obtained is used without additional purification in the following stage.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06809088B2 |
| 출처 데이터셋 | uspto-grants-2004_10 |
| ORD ID | ord-a2c4d1ad5c0049ed90be11c40f056869 |
| 출처 메모 | uspto-grants-2004_10 |