(2-Methoxy-5-methylphenyl)(phenyl)methanone → 4-Hydroxy-3-(1-phenyl-vinyl)-benzoic acid methylester

HRID 394000

반응식

HRID 394000 반응식
COC1C=CC(C)=CC=1C(C1C=CC=CC=1)=O.[CH2:18]([O:20][C:21](=[O:44])[C:22]1[CH:27]=[CH:26][C:25]([O:28]CC2C=CC=CC=2)=[C:24]([C:36]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[CH2:37])[CH:23]=1)C>>[CH3:18][O:20][C:21](=[O:44])[C:22]1[CH:27]=[CH:26][C:25]([OH:28])=[C:24]([C:36]([C:38]2[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=2)=[CH2:37])[CH:23]=1

참가 물질

3

반응물 2

HCID 249273(2-Methoxy-5-methylphenyl)(phenyl)methanoneHCID 235330294-Benzyloxy-3-(1-phenyl-vinyl)-benzoic acid ethylester4회

생성물 1

HCID 226484304-Hydroxy-3-(1-phenyl-vinyl)-benzoic acid methylester

실험 절차

1H-NMR (400 MHz, CDCl3): δ [ppm]=3.84 (s, 3H, CH3), 5.42 (d, 2J=1.0 Hz, 1H, ═CH2), 5.88 (d, 2J=1.0 Hz, 1H, ═CH2), 6.97 (d, 3J=8.5 Hz, 1H, PhH), 7.32 (m, 5H, PhH), 7.88 (d, 4J=2.3 Hz, 1H, PhH), 7.94 (dd, 3J=8.5 Hz, 4J=2.3 Hz, 1H, PhH). 13C-NMR (100 MHz, CDCl3): δ [ppm]=51.9 (CH3), 115.8 (CHarom), 117.4 (═CH2), 122.4 (Cqarom), 126.8 (2×CHarom), 127.6 (Cqarom), 128.7 (CHarom), 128.7 (2×CHarom), 131.3 (CHarom), 132.4 (CHarom), 138.8 (Cqarom), 144.3 (Cqolefin), 157.3 (Cqarom), 166.8 (COOMe). MS (EI, 70EV): m/z [%]=254 (M+, 5), 253 (7), 239 (3), 223 (1), 165 (1), 152 (1), 131 (1), 120 (22), 105 (44), 91 (100), 77 (37), 65 (13), 59 (16), 51 (20), 45 (17).

출처 및 근거

ORD 기록
ord-3e3520697a3946e3a20f779332e656ca
출처 데이터셋
uspto-grants-2004_10
특허 번호
US06809225B2

연결된 노트

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