Formaldehyde → HCID 12149956, 화합물
반응식
Cl.[NH:2]1[CH2:7][CH2:6][CH2:5][CH:4]([CH2:8][NH:9][C:10]([C@H:12]2[CH2:16][CH2:15][CH2:14][N:13]2[C:17]([C@@H:19]2[CH2:23][CH2:22][CH2:21][N:20]2[C:24](=[O:45])[CH2:25][C:26]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[O:18])=[O:11])[CH2:3]1.[CH2:46]=O>>[CH3:46][N:2]1[CH2:7][CH2:6][CH2:5][CH:4]([CH2:8][NH:9][C:10]([C@H:12]2[CH2:16][CH2:15][CH2:14][N:13]2[C:17]([C@@H:19]2[CH2:23][CH2:22][CH2:21][N:20]2[C:24](=[O:45])[CH2:25][C:26]([C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[O:18])=[O:11])[CH2:3]1참가 물질
3
실험 절차
The title compound was prepared by a method similar to Step 7 of Example 1 using (2R)-N-(3-piperidylmethyl)-1-{(2S)-1-(3,3,3-triphenylpropanoyl)pyrrolidin-2-yl}carbonylpyrrolidine-2-carboxamide monohydrochloride and 37% aqueous formaldehyde solution. The compound was obtained as a white solid.
후처리
- customThe compound was obtained as a white solid
출처 및 근거
- ORD 기록
- ord-fed1dc78bad54c5f9bb7b34de5bd300e
- 출처 데이터셋
- uspto-grants-2004_10