7-[(1-tert-Butylpiperidin-4-ylidene)methyl]-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one → 7-[(1-tert-Butylpiperidin-4-yl)methyl]-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one
반응식
[C:1]([N:5]1[CH2:10][CH2:9][C:8](=[CH:11][C:12]2[CH:21]=[C:20]3[C:15]([CH2:16][N:17]([CH2:31][C:32]4[CH:37]=[CH:36][C:35]([O:38][CH3:39])=[CH:34][CH:33]=4)[C:18](=[O:30])[N:19]3[C:22]3[C:27]([Cl:28])=[CH:26][CH:25]=[CH:24][C:23]=3[Cl:29])=[C:14]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][C:41]=3[Cl:46])[CH:13]=2)[CH2:7][CH2:6]1)([CH3:4])([CH3:3])[CH3:2].ClC1C=CC=C(Cl)C=1N1C2C(=C(C3C=CC=CC=3Cl)C=C(C3CCC4(OCCO4)CC3)C=2)CNC1=O>>[C:1]([N:5]1[CH2:10][CH2:9][CH:8]([CH2:11][C:12]2[CH:21]=[C:20]3[C:15]([CH2:16][N:17]([CH2:31][C:32]4[CH:33]=[CH:34][C:35]([O:38][CH3:39])=[CH:36][CH:37]=4)[C:18](=[O:30])[N:19]3[C:22]3[C:27]([Cl:28])=[CH:26][CH:25]=[CH:24][C:23]=3[Cl:29])=[C:14]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][C:41]=3[Cl:46])[CH:13]=2)[CH2:7][CH2:6]1)([CH3:4])([CH3:2])[CH3:3]참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared from 7-[(1-tert-butylpiperidin-4-ylidene)methyl]-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one as described in INTERMEDIATE 72. Mass spectrum (ESI): 676.6 (M+1).