N,N,N-trimethylglycinium → HCID 18176951, 화합물

HRID 394494

반응식

HRID 394494 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][CH:7]=1.[C:14]1([CH2:20][O:21][C:22]([NH:24][C@H:25]([C:29]([O:31][C:32]([CH3:35])([CH3:34])[CH3:33])=[O:30])[CH2:26][CH2:27]O)=[O:23])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.C[N+](CC(O)=O)(C)C>>[CH3:35][C:32]([CH3:33])([O:31][C:29](=[O:30])[CH:25]([NH:24][C:22]([O:21][CH2:20][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:23])[CH2:26][CH2:27][O:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][CH:7]=1)[CH3:34]

참가 물질

4

반응물 3

HCID 248N,N,N-trimethylglyciniumHCID 1512675Methyl 3-(3-hydroxyphenyl)propionateHCID 10804815AG-H-14083

생성물 1

HCID 18176951HCID 18176951, 화합물수율 67.9%

실험 절차

The operation is carried out as in Preparation 1 (Method 2) starting from 270 mg of the phenol prepared in Stage A, 309 mg of 1,1-dimethyl-ethyl N-[(phenylmethoxy)carbonyl]-L-homoserinate and 616 mg of betaine. 320 mg of expected product is obtained.

후처리

  1. customThe operation is carried out as in Preparation 1 (Method 2)

출처 및 근거

ORD 기록
ord-cedc6fdd6cc44c19875c49c35baec381
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06602878B1

연결된 노트

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