5-[5-(4-bromophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-pyridinesulfonamide → 5-{5-[4-(1,3-Thiazol-4-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl}-2-pyridinesulfonamide
반응식
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:14]=[CH:15][C:16]([S:19]([NH2:22])(=[O:21])=[O:20])=[N:17][CH:18]=3)[N:11]=[C:10]([C:23]([F:26])([F:25])[F:24])[CH:9]=2)=[CH:4][CH:3]=1.BrC1C=CC(C2N([C:39]3C=C[C:42]([S:45](N)(=O)=O)=[N:43][CH:44]=3)N=C(C(F)(F)F)C=2Cl)=CC=1>>[S:45]1[CH:39]=[C:44]([C:2]2[CH:7]=[CH:6][C:5]([C:8]3[N:12]([C:13]4[CH:14]=[CH:15][C:16]([S:19]([NH2:22])(=[O:21])=[O:20])=[N:17][CH:18]=4)[N:11]=[C:10]([C:23]([F:24])([F:25])[F:26])[CH:9]=3)=[CH:4][CH:3]=2)[N:43]=[CH:42]1참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared according to the procedure of step 3 in the Example 4 using 5-[5-(4-bromophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-pyridinesulfonamide (Example 4, step 1), instead of 5-[5-(4-bromophenyl)-4-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-pyridinesulfonamide.