Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Iodophthalic anhydride → 3-Iodo-N-(1-methyl-3-methylthiopropyl)-phthalamic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Iodophthalic anhydride | HCID 282071 | — |
| 반응물 | 4-(Methylsulfanyl)butan-2-amine | HCID 22979404 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3-Iodo-N-(1-methyl-3-methylthiopropyl)-phthalamic Acid | HCID 18178020 | 89.2% |
반응 단계
To a suspension of 2.74 g of 3-iodophthalic anhydride in 8 ml of acetonitrile cooled with ice was slowly added dropwise a solution of 1.19 g of 1-methyl-3-methylthiopropylamine in 3 ml of acetonitrile. After completion of the dropping, a reaction was carried out at room temperature for 3 hours with stirring. After completion of the reaction, the deposited crystal was collected by filtration and washed with a small quantity of acetonitrile. Thus, 3.5 g of the objective compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06603044B1 |
| 출처 데이터셋 | uspto-grants-2003_08 |
| ORD ID | ord-44769b3aa80b4d76933f15c5015bfff4 |
| 출처 메모 | uspto-grants-2003_08 |