2-Chloro-4-iodoaniline → 3-[(2-Chloro-4-iodophenyl)amino]isonicotinic acid
반응식
[Cl:1][C:2]1[CH:8]=[C:7]([I:9])[CH:6]=[CH:5][C:3]=1[NH2:4].F[C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][N:19]=1)[C:14]([OH:16])=[O:15]>>[Cl:1][C:2]1[CH:8]=[C:7]([I:9])[CH:6]=[CH:5][C:3]=1[NH:4][C:17]1[CH:18]=[N:19][CH:11]=[CH:12][C:13]=1[C:14]([OH:16])=[O:15]참가 물질
3
실험 절차
Synthesized as intermediate 1 by reacting 15.7 mmol of 2-chloro-4-iodoaniline with 23.55 mmol 2-fluoroisonicotinic acid. LC/MS [(5.9 min; 376 (M+1)].
후처리
- customSynthesized as intermediate 1
- custom5.9 min
출처 및 근거
- ORD 기록
- ord-831f693a9c4b4cb1b2a7ca46a2896ab2
- 출처 데이터셋
- uspto-grants-2013_09
- 특허 번호
- US08524911B2
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