HCID 12988784, 화합물 → 1,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

HRID 395338노트

반응식

HRID 395338 반응식
[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([N+:17]([O-])=O)[CH:11]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1>CCO.[Pd]>[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]([NH2:17])[C:13]([NH2:16])=[CH:14][CH:15]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

참가 물질

4

반응물 1

HCID 12988784HCID 12988784, 화합물

생성물 1

HCID 129887851,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution 4-(2-morpholin-4-ylethoxy)-2-nitrophenylamine (1.0 eq) in EtOH was added Pd/C (0.1 eq). The reaction vessel was repeatedly purged with nitrogen, then stirred under a hydrogen atmosphere (1 atm) for 18 hours. The product was filter ed through a Celite plug, and the plug washed with EtOH. The diamine was used without purification. LC/MS m/z 238.3 (MH+), Rf 0.295 minutes.

후처리

  1. customThe reaction vessel was repeatedly purged with nitrogen
  2. filtrationThe product was filter
  3. washthe plug washed with EtOH
  4. customThe diamine was used without purification

출처 및 근거

ORD 기록
ord-f4ca8b85f75d47eaaf3115c77a1dab1e
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06605617B2

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