1-Chloro-4-iodobenzene → 11-(4-Chlorophenyl)undec-10-yn-1-ol

반응식

[CH2:1]([OH:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]#[CH:11].[Cl:13][C:14]1[CH:19]=[CH:18][C:17](I)=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([C:11]#[C:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][CH2:1][OH:12])=[CH:16][CH:15]=1

참가 물질

반응물 2

HCID 125101-Chloro-4-iodobenzene

HCID 7601510-Undecyn-1-ol

생성물 1

HCID 2267810711-(4-Chlorophenyl)undec-10-yn-1-ol

실험 절차

In a manner described in Example 18 above, 10-undecyn-1-ol was reacted with 1-chloro-4-iodobenzene to give the title compound; NMR (CDCl3) δ 1.21-1.50 (m, 10H), 1.50-1.65 (m, 4H), 2.36-2.41 (m, 2H), 3.61-3.66 (m, 2H), 7.16-7.31 (m, 4H).

출처 및 근거

ORD 기록: ord-f4fe4d74fb564c50b9ea7cfec2fb7333
출처 데이터셋: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06605628B1

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