2,3-Dimethoxyaniline → 1-(Tert-butoxycarbonyl)-4-(2,3-dimethoxyphenylamino)piperidine

HRID 395528노트

반응식

HRID 395528 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:15][O:16][C:17]1[C:23]([O:24][CH3:25])=[CH:22][CH:21]=[CH:20][C:18]=1[NH2:19]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:19][C:18]2[CH:20]=[CH:21][CH:22]=[C:23]([O:24][CH3:25])[C:17]=2[O:16][CH3:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 2396032,3-DimethoxyanilineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

생성물 1

HCID 225578701-(Tert-butoxycarbonyl)-4-(2,3-dimethoxyphenylamino)piperidine

실험 절차

1-(tert-Butoxycarbonyl)-4-piperidone (4.78 g) and 2,3-dimethoxyaniline (3.68 g) were condensed in the same manner as described in Preparation Example 37 to give the title compound.

후처리

  1. customcondensed in the same manner
  2. customas described in Preparation Example 37

출처 및 근거

ORD 기록
ord-2d60edcda598439db59e5a80ea3ebd75
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06605620B1

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