Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate → HCID 22557800, 화합물

HRID 395542

반응식

HRID 395542 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([C:34]2[CH:35]=[C:36]([CH:39]=[CH:40][CH:41]=2)[CH2:37]Cl)[CH:27]=[C:28]([O:32][CH3:33])[C:29]=1[O:30][CH3:31]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH:9]2[CH2:10][CH2:11][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:13][CH2:14]2)[CH2:37][C:36]2[CH:39]=[CH:40][CH:41]=[C:34]([C:26]3[CH:27]=[C:28]([O:32][CH3:33])[C:29]([O:30][CH3:31])=[C:24]([O:23][CH3:22])[CH:25]=3)[CH:35]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 11210451Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylateHCID 120211573-(3,4,5-Trimethoxyphenyl)benzyl chloride

생성물 1

HCID 22557800HCID 22557800, 화합물

실험 절차

4-(4-Bromophenyl)amino-1-(tert-butoxycarbonyl)piperidine (711 mg) and 3-(3,4,5-trimethoxyphenyl)benzyl chloride (586 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.

출처 및 근거

ORD 기록
ord-48e19d078dd84b7e90ad9ee1c46f78aa
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06605620B1

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