4-Chloroaniline → Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate

HRID 395543

반응식

HRID 395543 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:20][C:19]2[CH:21]=[CH:22][C:16]([Cl:15])=[CH:17][CH:18]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 78124-ChloroanilineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

생성물 1

HCID 1491503Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate

실험 절차

1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 4-chloroaniline (3.05 g) was treated in the same manner as described in Preparation Example 37 to give white powder of the title compound.

후처리

  1. customas described in Preparation Example 37

출처 및 근거

ORD 기록
ord-0c034d6498314785a1051f99fafd4361
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06605620B1

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