Lipoic acid → N-(4-{[amino(2-thienyl)methylidene]amino}phenyl)-2-(1,2-dithiolan-3-yl)acetamide
반응식
Cl.[S:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([NH:16][C:17](=[O:27])[CH2:18][CH2:19][CH2:20][CH2:21]C2CCSS2)=[CH:12][CH:11]=1)=[NH:8].C1[C@@H](CC(O)=O)[S:31][S:30]C1.S1CCC(CC(O)=O)S1.C1[C@@H](CCCCC(O)=O)SSC1>>[NH2:8][C:7](=[N:9][C:10]1[CH:11]=[CH:12][C:13]([NH:16][C:17](=[O:27])[CH2:18][CH:19]2[CH2:20][CH2:21][S:31][S:30]2)=[CH:14][CH:15]=1)[C:3]1[S:2][CH:6]=[CH:5][CH:4]=1참가 물질
5
실험 절차
The experimental protocol used is the same as that described for compound 1, with trisnorlipoic acid [or 2-(1,2-dithiolan-3-yl)acetic acid] (prepared according to Tetrahedron Letters, (1997), 38, 33, 5785) replacing lipoic acid. Yellow foam.