Phthalide → 1,2-Benzenedimethanol

HRID 39622

반응식

HRID 39622 반응식
[C:1]1([C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][O:3]1)=[O:2].[H][H]>O1CCCC1>[C:5]1([CH2:4][OH:3])[C:10]([CH2:1][OH:2])=[CH:9][CH:8]=[CH:7][CH:6]=1

참가 물질

4

반응물 2

HCID 6885PhthalideHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 691531,2-Benzenedimethanol

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Phthalide (5 mmol), a ruthenium complex 1 (0.025 mmol), and tetrahydrofuran (2 mL) were charged into a 100-mL autoclave equipped with a stirrer. Then, the mixture was subjected to hydrogenation at a hydrogen pressure of 5 MPa at 100° C. for 16 hours. The reaction liquid was analyzed by gas chromatography. As a result, 1,2-benzenedimethanol was obtained at a conversion rate of 66% and a selectivity of 99% or more.

후처리

  1. customequipped with a stirrer
  2. customThe reaction liquid

출처 및 근거

ORD 기록
ord-abdaff8d3dc44bac983ca04b5b92d38e
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08524953B2

연결된 노트

불러오는 중…