Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propargyl bromide → 7-Propynyloxyflavone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propargyl bromide | HCID 7842 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 7-Hydroxyflavone | HCID 5281894 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 7-Propynyloxyflavone | HCID 18171843 | — |
반응 단계
A mixture of 7-hydroxyflavone (2.38 g, 0.01 mol), K2CO3 (2.8 g, 0.02 mol), Kl (0.166 g, 0.001 mol), propargyl bromide (1.78 g, 0.015 mol) and acetone (100 mL) was refluxed 10 h and hot filtered. The solvent was evaporated and the residue was crystallized by toluene. This yields 2.58 g of a product with the following characteristics: m.p. 199-200° C.; 1H NMR (CDC13) δ: 2.6 (m, 1H), 4.8 (s, 2H), 6.75-8.18 (m, 9H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06608089B2 |
| 출처 데이터셋 | uspto-grants-2003_08 |
| ORD ID | ord-bd3a5c6268414d7c95b108d5ce7466a1 |
| 출처 메모 | uspto-grants-2003_08 |