Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[5-chloro-2-(4-isopropylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

HRID 396459노트

반응식

HRID 396459 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:14]S(C2C=CC=CC=2)(=O)=O)=[C:6]([CH:13]=1)/[CH:7]=[CH:8]/[C:9]([O:11][CH3:12])=[O:10].Br[CH2:25][C:26]([C:28]1[CH:33]=[C:32]([CH:34]([CH3:36])[CH3:35])[CH:31]=[CH:30][N:29]=1)=[O:27]>>[CH3:12][O:11][C:9](=[O:10])[CH2:8][C:7]1[C:6]2[C:5](=[CH:4][CH:3]=[C:2]([Cl:1])[CH:13]=2)[NH:14][C:25]=1[C:26]([C:28]1[CH:33]=[C:32]([CH:34]([CH3:36])[CH3:35])[CH:31]=[CH:30][N:29]=1)=[O:27]

참가 물질

3

반응물 2

HCID 11187263Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 230032652-Bromoacetyl-4-isopropylpyridine

생성물 1

HCID 23003495Methyl[5-chloro-2-(4-isopropylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

실험 절차

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(penylsulfonylamino)cinnamate (Example 36, step 3) and 2-bromoacetyl-4-isopropylpyridine (Preparation is described in Example 61).

출처 및 근거

ORD 기록
ord-fd5d9a815a064bf8913f4e7c71c58093
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06608070B1

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