1-(4-Chloro-pyridin-2-yl)-ethanone → 2-Acetyl-4-(tert-butyldimethylsilyloxymethyl)pyridine

반응식

[Si:1]([O:8][CH2:9]C1C=CN=C(C#N)C=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[C:18]([C:21]1[CH:26]=[C:25](Cl)[CH:24]=[CH:23][N:22]=1)(=[O:20])[CH3:19]>>[C:18]([C:21]1[CH:26]=[C:25]([CH2:9][O:8][Si:1]([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2])[CH:24]=[CH:23][N:22]=1)(=[O:20])[CH3:19]

참가 물질

반응물 2

HCID 130119861-(4-Chloro-pyridin-2-yl)-ethanone

HCID 145414484-(Tert-butyldimethylsilyloxymethyl)pyridinecarbonitrile

생성물 1

HCID 230033972-Acetyl-4-(tert-butyldimethylsilyloxymethyl)pyridine

실험 절차

The title compound was prepared from 4-(tert-butyldimethylsilyloxymethyl)pyridinecarbonitrile (A. Hadri et al., J. Heterocycl. Chem., 1993, 30, 631) according to the procedure for preparing 2-acetyl-4-chloropyridine described in Example 33.

출처 및 근거

ORD 기록: ord-f3be48cd045946b28da30988357d4806
출처 데이터셋: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06608070B1

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