Sulfanilamide → 4-sulfamoyl-N-[4-(2-furyl)benzylidene]aniline

HRID 396760노트

반응식

HRID 396760 반응식
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][CH:11]=[CH:12][CH:13]=2)=[CH:5][CH:4]=1)=O.[S:14]([NH2:24])(=[O:23])([C:16]1[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=1)=[O:15]>C(O)C>[S:14]([C:16]1[CH:21]=[CH:20][C:19]([N:22]=[CH:1][C:3]2[CH:8]=[CH:7][C:6]([C:9]3[O:10][CH:11]=[CH:12][CH:13]=3)=[CH:5][CH:4]=2)=[CH:18][CH:17]=1)(=[O:15])(=[O:23])[NH2:24]

참가 물질

4

반응물 2

HCID 5333SulfanilamideHCID 27722954-(Furan-2-yl)benzaldehyde

생성물 1

HCID 223167314-sulfamoyl-N-[4-(2-furyl)benzylidene]aniline

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 2-(4-formylphenyl)furan (0.335 g, 1.95 mmol, prepared according to the method of Heterocycles, 1990, 31, 1951), sulfanilamide (0.336 g, 1.95 mmol) in ethanol (8 mL) was heated at reflux temperature for 2.5 hour. After cooling to room temperature, the crystals which collected by filtration and washed with ethanol to give the subtitle compound (0.378 g).

후처리

  1. customprepared
  2. temperaturewas heated
  3. temperatureat reflux temperature for 2.5 hour
  4. filtrationthe crystals which collected by filtration
  5. washwashed with ethanol

출처 및 근거

ORD 기록
ord-e9989f4e77d143e39f8802e51f6cd8e4
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06608095B2

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