Iodine → HCID 69364178, 화합물

HRID 397327노트

반응식

HRID 397327 반응식
[CH3:1][O:2][C:3](=[O:12])[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([F:11])[CH:6]=1.C([Li])(CC)C.[I:18]I>O1CCCC1>[CH3:1][O:2][C:3](=[O:12])[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([F:11])[C:6]=1[I:18]

참가 물질

5

반응물 3

HCID 807IodineHCID 3358980Methyl N-(3-fluorophenyl)carbamateHCID 178418400CID 53628100

생성물 1

HCID 69364178HCID 69364178, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

The starting material (3-fluoro-2-iodo-phenyl)-carbamic acid methyl ester was prepared from (3-fluoro-phenyl)-carbamic acid methyl ester by double deprotonation with sec.butyllithium in tetrahydrofuran at −78° C. followed by reaction with iodine. m.p.:80-82° C.

출처 및 근거

ORD 기록
ord-851486e0533a47ee84583327ef5d6ac7
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06610685B2

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