HCID 23000218, 화합물 → HCID 23000253, 화합물
반응식
[C:1]([N:4]([C:10]1[N:15]=[CH:14][CH:13]=CN=1)[CH2:5][CH2:6][CH2:7][C:8]#[CH:9])(=[O:3])[CH3:2]>[N+](C1C=CC=CC=1)([O-])=O>[C:1]([N:4]1[C:10]2[C:7](=[C:8]([CH3:9])[CH:13]=[CH:14][N:15]=2)[CH2:6][CH2:5]1)(=[O:3])[CH3:2]참가 물질
3
실험 절차
A solution of 2-(N-acetyl-N-pent-4-ynylamino)pyrimidine (3.49 g, 17.2 mmol) in nitrobenzene (35 mL) was heated under argon at 180° C. for 2 days. The reaction mixture was cooled and loaded directly onto a dry silica get column. The column was first eluted with methylene chloride to wash off the nitrobenzene and then was eluted with ether to give after evaporation in vacuo to give the title compound as a pale yellow solid:
후처리
- temperatureThe reaction mixture was cooled
- customget column
- washThe column was first eluted with methylene chloride
- washto wash off the nitrobenzene
- washwas eluted with ether
- customto give
- customafter evaporation in vacuo
출처 및 근거
- ORD 기록
- ord-4660dcf9e4ad498fa43053eaf3ddf8ee
- 출처 데이터셋
- uspto-grants-2003_08
- 특허 번호
- US06610692B1
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