Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanesulfonic Acid → Cholesta-1,5,7-trien-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanesulfonic Acid | HCID 6395 | — |
| 반응물 | Isopropenyl acetate | HCID 7916 | — |
| 반응물 | 1,4,6-Cholestatrien-3-one | HCID 107390 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Cholesta-1,5,7-trien-3-ol | HCID 18611553 | 61.2% |
반응 단계
To a mixture of 19 g (0.05 mol) of cholesta-1,4,6-trien-3-one (I), 4.8 g (0.05 mol) of methanesulfonic acid and 200 g (2 mol) of isopropenyl acetate were added 200 ml of toluene, and the resulting mixture was then heated under reflux for 6 hours. After completion of the reaction, the same treatment as in Example 1 was carried out to yield 11.7 g of cholesta-1,5,7-trien-3-ol (IV). The yield was 61%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04723045 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-d91476894bba4ff4b3f1ab9b2aac825a |
| 출처 메모 | uspto-grants-1988_02 |