Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4,6-Dichloro-2-methyl-5-nitropyrimidine → 4,6-Dichloro-2-methylpyrimidin-5-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4,6-Dichloro-2-methyl-5-nitropyrimidine | HCID 83192 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 4,6-Dichloro-2-methylpyrimidin-5-amine | HCID 736674 | — |
반응 단계
The third intermediate, 4,6-dichloro-2-methyl-5-nitropyrimidine is hydrogenated over Raney-Ni as a 10% to 30% solution in toluene to afford the corresponding compound, 4,6-dichloro-2-methyl-5-aminopyrimidine, as a fourth intermediate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05816260 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-b8efa4f6156f4b12be49de0edf7b530d |
| 출처 메모 | uspto-grants-1998_10 |