Propionyl chloride → 5-(N-[propionyl]amino)-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

HRID 398929

반응식

HRID 398929 반응식
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.[C:19](Cl)(=[O:22])[CH2:20][CH3:21]>>[C:19]([NH:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1)(=[O:22])[CH2:20][CH3:21]

참가 물질

3

반응물 2

HCID 62324Propionyl chlorideHCID 117706865-Amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

생성물 1

HCID 196015525-(N-[propionyl]amino)-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

실험 절차

Beginning with 0.015 gm (0.061 mMol) 5-amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.007 mL (0.080 mMol) propionyl chloride, the title compound was prepared essentially by the procedure described in Example 7.

출처 및 근거

ORD 기록
ord-f7cfe00435284ce78329218c4196e557
출처 데이터셋
uspto-grants-1998_10
특허 번호
US05817671

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