2-((5-Methoxy-1H-indol-6-yl)oxy)-N,N-dimethylethan-1-amine → 1-(4'-Acetyl-3'-methylbiphenyl-4-carbonyl)-6-(2-dimethylaminoethoxy)-5-methoxy-1H-indole
반응식
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16](O)=[O:17])=[CH:12][CH:11]=2)=[CH:6][C:5]=1[CH3:19])(=[O:3])[CH3:2].[CH3:20][N:21]([CH3:36])[CH2:22][CH2:23][O:24][C:25]1[CH:33]=[C:32]2[C:28]([CH:29]=[CH:30][NH:31]2)=[CH:27][C:26]=1[O:34][CH3:35]>>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]([C:16]([N:31]3[C:32]4[C:28](=[CH:27][C:26]([O:34][CH3:35])=[C:25]([O:24][CH2:23][CH2:22][N:21]([CH3:20])[CH3:36])[CH:33]=4)[CH:29]=[CH:30]3)=[O:17])=[CH:14][CH:15]=2)=[CH:6][C:5]=1[CH3:19])(=[O:3])[CH3:2]참가 물질
3
실험 절차
The title compound was prepared from 4'-acetyl-3'-methylbiphenyl-4-carboxylic acid (D21) and 6-(2-dimethylaminoethoxy)-5-methoxy-1H-indole (D13) using a similar procedure to Example 4 as an off-white solid mp 125°-127° C. (36%).
출처 및 근거
- ORD 기록
- ord-d0c3a23c900647568b2db0dfb1fc4fdc
- 출처 데이터셋
- uspto-grants-1998_10
- DOI