2-((5-Methoxy-1H-indol-6-yl)oxy)-N,N-dimethylethan-1-amine → 1-(4'-Cyano-2'-methylbiphenyl-4-carbonyl)-6-(2-dimethylaminoethoxy)-5-methoxy-1H-indole
반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([OH:17])=O)=[CH:11][CH:10]=2)=[C:5]([CH3:18])[CH:4]=1)#[N:2].[CH3:19][N:20]([CH3:35])[CH2:21][CH2:22][O:23][C:24]1[CH:32]=[C:31]2[C:27]([CH:28]=[CH:29][NH:30]2)=[CH:26][C:25]=1[O:33][CH3:34].C(C1C=CC(C2C=CC(C(O)=O)=CC=2)=CC=1C)(=O)C>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[CH:11][C:12]([C:15]([N:30]3[C:31]4[C:27](=[CH:26][C:25]([O:33][CH3:34])=[C:24]([O:23][CH2:22][CH2:21][N:20]([CH3:19])[CH3:35])[CH:32]=4)[CH:28]=[CH:29]3)=[O:17])=[CH:13][CH:14]=2)=[C:5]([CH3:18])[CH:4]=1)#[N:2]참가 물질
4
실험 절차
The title compound was prepared from 4'-cyano-2'-methylbiphenyl-4-carboxylic acid (D15) and 6-(2-dimethylaminoethoxy)-5-methoxy-1H-indole (D13) using a similar procedure to Example 4 as a white solid mp 140°-142° C. (42%).
출처 및 근거
- ORD 기록
- ord-917b972dc4ab4b939179bcd49e8b3f41
- 출처 데이터셋
- uspto-grants-1998_10
- 특허 번호
- US05817833
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