Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 1,3,3-Trichloro-2-methyl-7-oxabicyclo[4.1.0]heptane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 1-Methyl-2,2,6,6-tetrachlorocyclohexanol | HCID 18970952 | — |
| 반응물 | 1,3-Dichloro-3-fluoro-7-oxabicyclo[4.1.0]heptane | HCID 18970966 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1,3,3-Trichloro-2-methyl-7-oxabicyclo[4.1.0]heptane | HCID 18970971 | 95.5% |
반응 단계
The same procedure was employed as for the preparation of 2e in Example 17: it was performed with 3.97 g (15.75 mmol) of crude alcohol 1j, 20 cm3 of distilled water and 2.4 g (60 mmol) of sodium hydroxide; reaction time was 1 h 15 min; ether extraction (5×40 cm3); 3.29 g of epoxide 2h were obtained having a 95.5% yield based on the ketone (macrobore GC purity>99%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05817890 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-fa28d522f0fe44109c518a5623e6ed9b |
| 출처 메모 | uspto-grants-1998_10 |