Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-6,7-dimethoxyquinazoline hydrochloride → 4-[3-Chloro-4-(2-pyridylcarbonyl)anilino]-6,7-dimethoxyquinazoline dihydrochloride salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-6,7-dimethoxyquinazoline hydrochloride | HCID 22022161 | — |
| 반응물 | 4-Amino-2-chlorophenyl 2-pyridyl ketone | HCID 53735793 | — |
| 생성물 | 4-[3-Chloro-4-(2-pyridylcarbonyl)anilino]-6,7-dimethoxyquinazoline dihydrochloride salt | HCID 18967560 | 45% |
반응 단계
Using an analogous procedure to that described in Example 1, 4-amino-2-chlorophenyl 2-pyridyl ketone was reacted with 4-chloro-6,7-dimethoxyquinazoline hydrochloride to give 4-[3-chloro-4-(2-pyridylcarbonyl)anilino]-6,7-dimethoxyquinazoline dihydrochloride salt in 45% yield, m.p. 255°-258° C.;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821246 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-1dbc9b5e32d04fd0b15183cdd8a71ea2 |
| 출처 메모 | uspto-grants-1998_10 |