Sulfabenz → HCID 18967621, 화합물

HRID 399464

반응식

HRID 399464 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.Cl.[Cl:19][C:20]1[C:29]2[C:24](=[CH:25][C:26]([O:32][CH3:33])=[C:27]([O:30][CH3:31])[CH:28]=2)[N:23]=[CH:22][N:21]=1>>[ClH:19].[CH3:31][O:30][C:27]1[CH:28]=[C:29]2[C:24](=[CH:25][C:26]=1[O:32][CH3:33])[N:23]=[CH:22][N:21]=[C:20]2[NH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](=[O:10])(=[O:9])[NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 31390SulfabenzHCID 220221614-Chloro-6,7-dimethoxyquinazoline hydrochloride

생성물 1

HCID 18967621HCID 18967621, 화합물수율 95%

실험 절차

Using an analogous procedure to that described in Example 1, 4-amino-N-phenylbenzenesulphonamide was reacted with 4-chloro-6,7-dimethoxyquinazoline hydrochloride to give 6,7-dimethoxy-4-[4-(N-phenylsulphamoyl)anilino]quinazoline hydrochloride salt in 95% yield,

출처 및 근거

ORD 기록
ord-3d06dbb8567040298524dc7c818aa443
출처 데이터셋
uspto-grants-1998_10
특허 번호
US05821246

연결된 노트

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