Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 4-methoxypyridine-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Methyl 4-Chloropicolinate | HCID 820890 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 생성물 | Methyl 4-methoxypyridine-2-carboxylate | HCID 1519345 | — |
반응 단계
A mixture of methyl 4-chloropyridine-2-carboxylate (3.7 g), sodium metal (0.5 g) and methanol (100 ml) was stirred and heated to reflux for 8 hours. The mixture was evaporated and the residue was partitioned between ethyl acetate and water. The organic phase was dried (MgSO4) and evaporated to give methyl 4-methoxypyridine-2-carboxylate (3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821246 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-20b68bca3eea4b289fb28d8fe1e448c8 |
| 출처 메모 | uspto-grants-1998_10 |